This is BioStrand Retrieve and Relate

Retrieve and Relate  is a multi-facetted application for genetic sequence analysis.
Our unique and revolutionary approach tears down the existing barriers between silos and gives you the most complete and comprehensive results possible.

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Capabilities that simplify genetic research

Simultaneous multi-domain searching

Search by text and bio-sequences

Lightning quick processing speed

High accuracy by exact matching

What sets R&R apart?

Better insights
More control
Managing costs
Speed up innovation

Better insights

R&R is your omics research companion capable of quick comparisons and in-depth data exploration.

We uncover the substantial amount of knowledge and results that remain untapped by limitations in current technology.

We do all the heavy lifting, giving you the time and freedom to focus on what is really important in your research - discover new relationships in your data and make substantial progress in less time:

  • Search simultaneously through all publicly available omics data sources (public databases, sequences in patent data, gen banks) and even combine this with your own data.
  • No limitations. Start your search without having to apply a single form of prefiltering or parameter setting that restricts your search space. Search by sequence, text input or file input. Receive immediate return of results on 3 levels: DNA, RNA and AA. If your input is a DNA sequence or a text-based search, your results are immediately displayed on the three levels.
  • Your results are well organised. Filter the results that are relevant for you starting from a comprehensive global overview. Slice and dice your results without losing track.

More control

We like to keep things simple but comprehensive. So, R&R is intuitive and user-friendly. Our paradigm shifting technology allows for exact matching. As a consequence, accuracy and relevance of results is unprecedented.

Not only bioinformaticians, but also all primary researchers working with omics data can use R&R.

As a researcher, you do not need to build complex pipelines first and find your way in a disparate tool environment. From start to finish, you have control over your data and can run analyses easily. 

As a bioinformatician you now have a fast and easy access to multiple databases which greatly reduces the effort of compiling a feature space for machine learning applications

Managing costs

No need for supercomputers or extensive and expensive cloud service subscriptions to run your analyses.

Our licences have a fixed fee, allowing you to fully control your budget. No hidden charges or surprises.

 

Speed up innovation

‘Data in, instant results out’ is no longer an empty statement. The scalability of the BioStrand technology enables the handling of extremely large datasets at high speed.

We provide you with a large number of relevant results, presented transparently. Knowledge extraction is made easier than ever.

So, when it comes to unravelling the secrets hidden in these massive amounts of unexplored data, you can accept any challenge!

If you are responsible for an R&D unit, BioStrand allows you to make decisions about the start or end of research projects sooner. Meaning, budgets can be allocated more efficiently.

You speed up your research.

"BioStrand is the missing link in the development of our innovations. It accelerates and improves the process, and pro-actively enables new types of developments. A great tool for bio-informaticians and genetic experts. It also helps the less specialised researchers like myself to accurately direct and guide the experts and their research."

Guy Van Daele
R&D Manager Globachem

R&R Professional and Enterprise

Professional

R&R Professional makes your life as a researcher much easier and allows you to focus and discover new findings. Search through the included publicly available databases, and receive immediate translations between DNA, RNA, and proteins. Next to sequence input, you can search with free text. You get continuous updates from the moment they are available.

Enterprise

R&R Enterprise brings all the data together without losing true oversight, giving you all the insights that are needed to easily build on your team’s research. With the included ‘bring your own data’ R&R extension, you have the advantage of simultaneously searching through all publicly available omics data, as well as through your own data. Your own proprietary data is securely stored and can only be accessed by you.

Retrieve and Relate is the go-to tool for all genetic research related questions

Main features

Search

BioStrand’s approach to search queries is very different from today’s standard

Our tool’s search bar enables you to start searching DNA, RNA or Proteins as well as free text - meaning there is no need to set any preliminary search parameters or filters which restrict the search space.

Simply paste a biological sequence or certain functions, species or other metadata in the search bar to find similar sequences. Your results are immediately displayed on 3 levels: DNA, RNA and AA

Filter

Our philosophy is to keep things transparent and comprehensive

Start with a global overview in which you decide how to drill down into the details that suit your research question.

Filter with multiple granularities.

Exclude or include specific parameters and sequence details such as DNA, RNA, proteins or patents with an easy tabular function.

Text-based Search

Unique capabilities based on the patented concepts of HyftsTM

These HyftsTM allow for combining textual data with biological sequence data.

In other words, searching by textual data is intrinsically linked to searching biological sequence data meaning that any other approaches are now obsolete.

With this, we increase the speed of search to results.

Unique results presentation

Quickly drill down and extrapolate through the results

In the Explorer View, select or combine multiple dimensions such as taxonomy or ontology to quickly discover novelty functional relationships.

Obtain an overview for annotating functions, or discover other useful visual applications such as ontology maps, frequency tables or multiple sequence alignment views.

Alignment View

Sequence level details displayed

The Alignment View allows for a microscopic view down to the sequence level.

Never lose track of filters and change or apply additional filters easily as needed, even by free text search.

Switch between Alignment View and List View functions with the simple navigation bar, while continuously keeping selected filters in place.

Results List

A handy overview bar helps to keep track of chosen filters which makes it easy to apply and reapply the filters.

You can simply click on a filter and it immediately shows the relevant insights and results.

Each main domain is associated with a specific filter.

Multiple data sources

Remove limits for similarity and variant discovery

There is no limit to the number of databases that can be accessed or added, even from third party providers - meaning they all can be searched simultaneously.

Access and search the three different sources of genetic data: public databases, pay-to-access databases and your own databases, allowing for more comprehensive and faster results.

Search

BioStrand’s approach to search queries is very different from today’s standard

Our tool’s free search bar enables you to start searching DNA, RNA or Proteins as well as free text - meaning there is no need to set any preliminary search parameters or filters which restrict the search space.

Simply paste a biological sequence or certain functions, species or other metadata in the search bar to find similar sequences. Your results are immediately displayed on 3 levels: DNA, RNA and AA

Filter

Our philosophy is to keep things transparent and comprehensive

Start with a global overview in which you decide how to drill down to the details that suit your research question.

Filter with multiple granularities.

Exclude or include specific parameters and sequence details such as DNA, RNA, proteins, and patents with an easy tabular function.

Text-based Search

Unique capabilities based on the patented concepts of HyftsTM

These HyftsTM allow for combining textual data with biological sequence data.

In other words, searching by textual data is intrinsically linked to searching biological sequence data meaning that any other approaches are now absolete.

With this, we increase the speed of search to results.

Unique results presentation

Quickly drill down and extrapolate through the results

In the Explorer View, select or combine multiple dimensions such as taxonomy or ontology to quickly discover novelty functional relationships.

Obtain an overview for annotating functions, or discover other useful visual applications such as ontology maps, frequency tables or multiple sequence alignment views.

Alignment View

Sequence level data sets specific to your needs

The Alignment View allows for a microscopical view down to the sequence level.

Never lose track of filters and change or apply additional filters easily as needed, even by free text search.

Switch between Alignment View and List View functions with the simple navigation bar, while continuously keeping selected filters in place.

Results List

A handy overview bar helps to keep track of chosen filters which makes it easy to apply and reapply the filters.

You can simply click on a filter and it immediately shows the relevant insights and results.

Each main domain is associated with a specific filter.

Multiple data sources

Remove limits for similarity and variant discovery

There is no limit to the number of databases that can be accessed or added, even from third party providers - meaning they all can be searched simultaneously.

Access and search the three different sources of genetic data: public databases, pay-to-access databases and your own databases, allowing for more comprehensive and faster results.

Technology

Smart applications –such as Face-Recognition Technology– recognise multiple features and translate them into a unique code representing one’s individual signature.

This unique facial signature is then matched to other images. By introducing a FRT-like approach to omics data analysis we can recognise genetic or amino-acid sequences in an instant. Detect patterns, and compare the reconstructed sequenced string with other omics data to uncover similarities and differences between subjects and species in mere seconds.

 

Using HYFTs™ BioStrand transforms the current methodology in omics analysis into exact matching and indexing.

HYFTs™ are signature sequences, structural anchor points in genetic code, which carry multiple layers of information. We use the HYFTs™ as a multilevel information network underpinning our data analysis.

With the BioStrand approach, a wide variety of analyses on omics data can be executed in one operation, at a lightning fast speed. Because we use exact matching, accuracy is unprecedented.

GSK meets Universities

 

Upcoming features

Nov2020

Update

Add self-owned databases to the search domains including biological and textual databases.

Dec2020

Update

Construct reports of your searches by combining different visual elements.

Jan2021

Upcoming

‘Relate' becomes even more advanced. Relate turns into a recommendation engine used for sequence annotation.

Input can either be a biological sequence or FASTQ/ FASTA file (or comparable). BioStrand’s technology processes the input and finds all known domains based on available public data.

In conjunction with the search principle of multi-domain comparisons the researcher is able to effectively identify domains in the sequence and simultaneously correlate these domains to other known databases.

How it is used

1. Sequence analysis

This operation consists of finding which part of the biological sequences are alike, and which part differs, during medical analysis and genome mapping processes.

2. Multiple sequence alignment

Align multiple sequences together to detect conserved regions.

3. Protein domain analysis

Find protein family/fold/structure annotation.

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